Erik ten Hag's team were sloppy in the first 45 minutes and after an early chance for Davy Klaassen, whose header hit the crossbar, the the chances dried up. With goals from Cordoba and Rommens, it was 2-0 at halftime.
Ajax improved slightly in the second half, making it 2-1, but were unable to find an equalizer.
Go Ahead Eagles - Ajax 2-1 (2-0)
18. Cordoba 1-0
45+3. Rommens 2-0
64. Berghuis 2-1
Ajax: Onana; Rensch (46. Mazraoui), Schuurs, Martínez, Blind; Álvarez (59. Gravenberch), Klaassen (59. Danilo), Berghuis; Antony (82. Kudus), Haller, Tadic